Pathophysiology I - UPWr Syllabus

Pathophysiology I

Educational subject description sheet

Basic information

Field of study: Veterinary Medicine
Speciality: -
Organizational unit: The Faculty of Veterinary Medicine
Study level: Long-cycle programme
Study form: Full-time
Education profile: General academic

Education cycle: 2025/26
Subject code: MD000000MWW-AJS.J8BO.1559.25
Lecture languages: english
Mandatory: mandatory
Block: major subjects (conducted) in foreign languages
Disciplines: Veterinary medicine
Subject related to scientific research: Yes
Subject shaping practical skills: No

Teacher responsible for the subject

Aleksandra Pliszczak-Król

Other teachers conducting classes

Aleksandra Pliszczak-Król

Period

Semester 4

Examination

graded credit

Activities and hours

lecture: 30

Standard groups

A. Basic sciences, B1. Clinical sciences

Number of ECTS points

3.0

Goals

C1	to familiarize students with basic paradigms and concepts related to the science of disease and disorders of homeostasis, dynamics of the processes deterimning the development of the disease.
C2	to familiarize students with the pathogenic effect of selected etiological factors and pathogenesis of diseases caused by them.

Subject's learning outcomes

Code	Outcomes in terms of	Effects	Examination methods
Knowledge – Student knows and understands:
W1	the principles and mechanisms underlying animal health, disease formation and their treatment - from the level of cells, through the organ, animal, to the entire animal population.	O.W1	written credit, oral credit, participation in discussion
W2	selected systemic disorders in pathological conditions.	O.W2	written credit, oral credit, participation in discussion
W3	the etiology, pathogenesis and clinical symptoms of diseases occurring in individual animal species, and knows the principles of therapeutic procedure.	O.W3	written credit, oral credit, participation in discussion
W4	the mechanism of neurohormonal regulation, aging and death.	A.W9	written credit, oral credit, participation in discussion
W5	the principles and mechanisms underlying animal health and disease formation at the level of cell, the organ and the entire animal body.	A.W10	written credit, oral credit, participation in discussion
W6	the correlation between factors (e.g. temperature, electricity, electromagnetic ionization, altitude) that disturb the balance between biological processes of the animal body and pathophysiological changes.	A.W11	written credit, oral credit, participation in discussion
W7	the pathophysiological changes occurring in cells, tissues, organs and systems of animals, as well as biological mechanisms, including immunological mechanisms, and therapeutic possibilities that allow recovery.	A.W12	written credit, oral credit, participation in discussion
W8	the Polish and Latin medical nomenclature in Pathophysiology.	A.W20	written credit, oral credit, participation in discussion
Skills – Student can:
U1	use the knowledge of the laws of physics in order to explain the impact of external factors (temperature, pressure, electromagnetic field, ionizing radiation) on the animal body.	A.U1	written credit, oral credit, participation in discussion
U2	describe changes in functioning of the organism in the situation of homeostasis disorders caused by exogenous and endogenous factors.	A.U4	written credit, oral credit, participation in discussion
U3	define physiological state as the animal's adaptation to the changing environmental factors.	A.U7	written credit, oral credit, participation in discussion
U4	listen and provide answers with the use of understandable language, appropriate to the given situation	A.U13	written credit, oral credit, participation in discussion
U5	understand the need of continuing education, in order to ensure continuous professional development	A.U21	written credit, oral credit, participation in discussion
U6	use Latin medical nomenclature to the extent necessary to understand and describe medical activities, as well as state of animal health, diseases, pathological changes and conditions	O.U8	written credit, oral credit, participation in discussion
Social competences – Student is ready to:
K1	exhibit responsibility for his/her decisions made in regard to the people, animals and the natural environment.	O.K1	written credit
K2	use the objective sources of information related to pathophysiology.	O.K4	written credit
K3	deepen his/her knowledge and improve skill in pathophysiology.	O.K8	written credit
K4	communicate with the co-workers and share knowledge	O.K9	written credit

Balance of ECTS points

Activity form	Activity hours*
lecture	30
exam / credit preparation	25
lesson preparation	30

Student workload	Hours 85	ECTS 3.0
Workload involving teacher	Hours 30	ECTS 1.0

* hour means 45 minutes

Study content

No.	Course content	Activities
1.	1. Pathophysiology as a science that integrates all knowledge of disease and modulates the "medical thinking." (2h) 2. Nozology - the science of disease in general. Health vs disease. Kinetics of functional and pathological regulation, compensation, adaptation. Disease as disorder of the body function regulations and the correlation between them, "vicious circle". Etiology of diseases. Main and secondary, exogenous and endogenous causes as factors that cause and modulate the disease status. (2h) 3. Pathogenesis, sanogenesis, Development of the disease (evolutio morbi). Mechanical factors as reasons of diseases - kinetosis, hypokinesis, akinesis. (2h) 4. Thermal factors. Pathogenesis of burn disease. (2h) 5. Electromagnetic radiation influence on the animal body. Electrical currents and sound waves (infrasound, audible sound, ultrasound) - influence on the animal body. (2h) 6. Biological pathogens. Mechanisms of microbiological infections. (2h) 7. Macro- and microclimate conditions as determinants of the diseases occurrence. Pathogenesis of acute and chronic altitude sickness. Disorders of thermoregulation and their determinants. Hypothermia, hyperthermia - systemic changes and their results. (2h) 8. Fever as an adaptive process. Etiopathogenesis, systemic changes, positive and negative aspects of fever. (2h) 9. Genetic factors in the etiopathogenesis of diseases. Constitution, condition and the formation of diseases. Predisposition to the occurrence of diseases. Aging and death. Aging, homeostasis and the occurrence of diseases. Specificity of veterinary geriatrics. (2h) 10. Metabolic disorders. Priority of tissues in access to nutrients. Endogenous and exogenous causes of metabolic disorders in animals. (2h) 11-12. Trace elements and micronutrients in allostasis. Etiopathogenesis and symptoms of micronutrient deficiencies in animals. (4h) 13-15. Vitamin disorders in animals (fat-soluble vitamins): Vitamins and their participation in the regulation of body metabolism. Factors that determinate of vitamin requirements. Hypovitaminosis and hypervitaminosis. Factors promoting disorders and consequences of vitamin deficiency in various animal species. Credit for the topics of lectures 1-12. (6h).	lecture

No.

Course content

Activities

1. Pathophysiology as a science that integrates all knowledge of disease and modulates the "medical thinking." (2h)

2. Nozology - the science of disease in general. Health vs disease. Kinetics of functional and pathological regulation, compensation, adaptation. Disease as disorder of the body function regulations and the correlation between them, "vicious circle". Etiology of diseases. Main and secondary, exogenous and endogenous causes as factors that cause and modulate the disease status. (2h)

3. Pathogenesis, sanogenesis, Development of the disease (evolutio morbi). Mechanical factors as reasons of diseases - kinetosis, hypokinesis, akinesis. (2h)

4. Thermal factors. Pathogenesis of burn disease. (2h)

5. Electromagnetic radiation influence on the animal body. Electrical currents and sound waves (infrasound, audible sound, ultrasound) - influence on the animal body. (2h)

6. Biological pathogens. Mechanisms of microbiological infections. (2h)

7. Macro- and microclimate conditions as determinants of the diseases occurrence. Pathogenesis of acute and chronic altitude sickness. Disorders of thermoregulation and their determinants. Hypothermia, hyperthermia - systemic changes and their results. (2h)

8. Fever as an adaptive process. Etiopathogenesis, systemic changes, positive and negative aspects of fever. (2h)

9. Genetic factors in the etiopathogenesis of diseases. Constitution, condition and the formation of diseases. Predisposition to the occurrence of diseases. Aging and death. Aging, homeostasis and the occurrence of diseases. Specificity of veterinary geriatrics. (2h)

10. Metabolic disorders. Priority of tissues in access to nutrients. Endogenous and exogenous causes of metabolic disorders in animals. (2h)

11-12. Trace elements and micronutrients in allostasis. Etiopathogenesis and symptoms of micronutrient deficiencies in animals. (4h)

13-15. Vitamin disorders in animals (fat-soluble vitamins): Vitamins and their participation in the regulation of body metabolism. Factors that determinate of vitamin requirements. Hypovitaminosis and hypervitaminosis. Factors promoting disorders and consequences of vitamin deficiency in various animal species. Credit for the topics of lectures 1-12. (6h).

lecture

Course advanced

Teaching methods:

educational film, problem-solving method, presentation / demonstration, discussion, lecture

Activities	Examination methods	Percentage in subject assessment
lecture	written credit, oral credit, participation in discussion	100%

Additional info

In the case of switching to distance education, it is possible to complete the course on the basis of online tests conducted on the selected educational platform.

Entry requirements

Completion of the course in: biochemistry, cell biology, histology and embriology, animal anatomy, animal physiology.

Literature

Obligatory

Zachary J.F. Pathologic basis of veterinary disease. ELSEVIER, 2017, 6th edition.
Cheville N.F. Introduction to Veterinary Pathology. BLACKWELL PUBLISHING, 2006, 3rd edition.
Dunlop R.H., Malbert Ch.h. Veterinary Pathophysiology. BLACKWELL PUBLISHING, 2004.
Stockham S.L., Scott M.A. Fundamentals of Veterinary Clinical Pathology. IOWA STATE PRESS. A Blackwell Publishing Company, 2002
McCance k.L., Huether S.E. Pathophysiology. The biologic basis for disease in adults and children. ELSEVIER, 2019, 8th edition.
Norris T.L. Porth’s Pathophysiology. Concepts of altered health states. Walters Kluwer, 2019.

Optional

Damjanov I. Pathophysiology. SAUNDERS. Elsevier, 2009.
Silbernagl S., lang F. Color atlas of Pathophysiology. THIEME, 2016, 3rd edition.
Harvey j.W. Veterinary Hematology. A diagnostic guide and color atlas. ELSEVIER, 2012.